Islet amyloid polypeptide does not suppress pancreatic cancer

Islet amyloid polypeptide does not suppress pancreatic cancer

Objectives: Pancreatic cancer risk is elevated approximately two-fold in type 1 and type 2 diabetes. Islet amyloid polypeptide (IAPP) is an abundant beta-cell peptide hormone that declines with diabetes progression. IAPP has been reported to act as a tumour-suppressor in p53-deficient cancers capabl...

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Bibliographic Details
Main Authors: Austin J. Taylor, Evgeniy Panzhinskiy, Paul C. Orban, Francis C. Lynn, David F. Schaeffer, James D. Johnson, Janel L. Kopp, C. Bruce Verchere
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Molecular Metabolism
Subjects:
Islet amyloid polypeptide
Amylin
Pancreatic ductal adenocarcinoma
Diabetes
Tumor suppressor
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877823000017

Internet

http://www.sciencedirect.com/science/article/pii/S2212877823000017

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