Acquired immunological imbalance after surgery with cardiopulmonary bypass due to epigenetic over-activation of PU.1/M-CSF

Acquired immunological imbalance after surgery with cardiopulmonary bypass due to epigenetic over-activation of PU.1/M-CSF

Abstract Background It has been shown that severe insult to the immune system may trigger prolonged macrophage characteristics associated with excessive release of monocyte colony stimulating factor (M-CSF). However, it is unclear how persistent is the macrophage-like characteristics in circulating...

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Bibliographic Details
Main Authors: Krzysztof Laudanski, Mateusz Zawadka, Jacek Polosak, Jaymin Modi, Matthew DiMeglio, Jacob Gutsche, Wilson Y. Szeto, Monika Puzianowska-Kuznicka
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Translational Medicine
Subjects:
Epigenetics
Cardiopulmonary bypass
PU.1
Monocytes
Granulocyte colony stimulating factor
Online Access:http://link.springer.com/article/10.1186/s12967-018-1518-3

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http://link.springer.com/article/10.1186/s12967-018-1518-3

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