Differential methylation patterns in lean and obese non-alcoholic steatohepatitis-associated hepatocellular carcinoma

Abstract Background Nonalcoholic fatty liver disease affects about 24% of the world’s population and may progress to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma (HCC). While more common in those that are obese, NASH-HCC can develop in lean individuals. The mechanisms...

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Bibliographic Details
Main Authors: Emma Hymel, Kurt W. Fisher, Paraskevi A. Farazi
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-10389-7