Human neutrophil cytoskeletal dynamics and contractility actively contribute to trans-endothelial migration.

Transmigration through the endothelium is a key step in the immune response. In our recent work, the mechanical properties of the subendothelial matrix and biophysical state of the endothelium have been identified as key modulators of leukocyte trans-endothelial migration. Here, we demonstrated that...

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Bibliographic Details
Main Authors: Kimberly M Stroka, Heather N Hayenga, Helim Aranda-Espinoza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3634075?pdf=render