IDO and Kynurenine Metabolites in Peripheral and CNS Disorders
The importance of the kynurenine pathway in normal immune system function has led to an appreciation of its possible contribution to autoimmune disorders such as rheumatoid arthritis. Indoleamine-2,3-dioxygenase (IDO) activity exerts a protective function, limiting the severity of experimental arthr...
Hauptverfasser: | , , , , |
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Format: | Artikel |
Sprache: | English |
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Frontiers Media S.A.
2020-03-01
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Schriftenreihe: | Frontiers in Immunology |
Schlagworte: | |
Online Zugang: | https://www.frontiersin.org/article/10.3389/fimmu.2020.00388/full |