IDO and Kynurenine Metabolites in Peripheral and CNS Disorders

The importance of the kynurenine pathway in normal immune system function has led to an appreciation of its possible contribution to autoimmune disorders such as rheumatoid arthritis. Indoleamine-2,3-dioxygenase (IDO) activity exerts a protective function, limiting the severity of experimental arthr...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Yi-Shu Huang, Joy Ogbechi, Felix I. Clanchy, Richard O. Williams, Trevor W. Stone
Format: Artikel
Sprache:English
Veröffentlicht: Frontiers Media S.A. 2020-03-01
Schriftenreihe:Frontiers in Immunology
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Online Zugang:https://www.frontiersin.org/article/10.3389/fimmu.2020.00388/full