Evidence for a common high affinity binding site on glutathione S-transferase B for lithocholic acid and bilirubin.

Binding of lithocholic acid, bilirubin, and gossypol to glutathione S-transferase B (ligandin or transferase YaYc) was compared using four methods. Tryptophan quenching revealed a single high affinity site for bilirubin and gossypol but could not be used for lithocholic acid. Both displacement of th...

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Bibliographic Details
Main Authors: Y Sugiyama, A Stolz, M Sugimoto, N Kaplowitz
Format: Article
Language:English
Published: Elsevier 1984-11-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520344618