CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo

CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo

<p>Abstract</p> <p>Background</p> <p>Bacterial DNA containing motifs of unmethylated CpG dinucleotides (CpG-ODN) initiate an innate immune response mediated by the pattern recognition receptor Toll-like receptor 9 (TLR9). This leads in particular to the expression of pr...

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Bibliographic Details
Main Authors: Hoeft Andreas, Meyer Rainer, Mersmann Jan, Ehrentraut Heidi, Velten Markus, Schwederski Markus, Koch Alexander, Baumgarten Georg, Knuefermann Pascal, Zacharowski Kai, Grohé Christian
Format: Article
Language:English
Published: BMC 2007-10-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/8/1/72

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http://respiratory-research.com/content/8/1/72

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