Development of an orally delivered GLP-1 receptor agonist through peptide engineering and drug delivery to treat chronic disease

Development of an orally delivered GLP-1 receptor agonist through peptide engineering and drug delivery to treat chronic disease

Abstract Peptide therapeutics are increasingly used in the treatment of disease, but their administration by injection reduces patient compliance and convenience, especially for chronic diseases. Thus, oral administration of a peptide therapeutic represents a significant advance in medicine, but is...

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Bibliographic Details
Main Authors: Sergei Pechenov, Jefferson Revell, Sarah Will, Jacqueline Naylor, Puneet Tyagi, Chandresh Patel, Lihuan Liang, Leo Tseng, Yue Huang, Anton I. Rosenbaum, Kemal Balic, Anish Konkar, Joseph Grimsby, J. Anand Subramony
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01750-0

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https://doi.org/10.1038/s41598-021-01750-0

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