The Plasticity of Pancreatic β-Cells

Type 2 diabetes is caused by impaired insulin secretion and/or insulin resistance. Loss of pancreatic β-cell mass detected in human diabetic patients has been considered to be a major cause of impaired insulin secretion. Additionally, apoptosis is found in pancreatic β-cells; β-cell mass loss is ind...

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Bibliographic Details
Main Authors: Norikiyo Honzawa, Kei Fujimoto
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/4/218