Retinal Neuroprotection From Optic Nerve Trauma by Deletion of Arginase 2

Retinal Neuroprotection From Optic Nerve Trauma by Deletion of Arginase 2

Our previous studies have implicated expression of the mitochondrial isoform of the arginase enzyme arginase 2 (A2) in neurovascular injury during ischemic retinopathies. The aim of this study was to characterize the specific involvement of A2 in retinal injury following optic nerve crush (ONC). To...

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Bibliographic Details
Main Authors: Zhimin Xu, Abdelrahman Y. Fouda, Tahira Lemtalsi, Esraa Shosha, Modesto Rojas, Fang Liu, Chintan Patel, R. William Caldwell, Subhadra Priya Narayanan, Ruth B. Caldwell
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Neuroscience
Subjects:
arginase 2
retina
neuroprotection
optic nerve crush
brain derived neurotrophic factor
retinal ganglion cells
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00970/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.00970/full

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