DCE-MRI of Sunitinib-Induced Changes in Tumor Microvasculature and Hypoxia: A Study of Pancreatic Ductal Adenocarcinoma Xenografts

DCE-MRI of Sunitinib-Induced Changes in Tumor Microvasculature and Hypoxia: A Study of Pancreatic Ductal Adenocarcinoma Xenografts

The purpose of this study was dual: to investigate (a) whether sunitinib may induce changes in tumor microvasculature and hypoxia in pancreatic ductal adenocarcinoma (PDAC) and (b) whether any changes can be detected by DCE-MRI. Sunitinib-treated and untreated control tumors of two PDAC xenograft mo...

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Bibliographic Details
Main Authors: Catherine S. Wegner, Anette Hauge, Trude G. Simonsen, Jon-Vidar Gaustad, Lise Mari K. Andersen, Einar K. Rofstad
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558618301799

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http://www.sciencedirect.com/science/article/pii/S1476558618301799

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