A modified protocol of the alloxan technique for the induction of diabetes mellitus in Wistar rats

The chemical induction of diabetes mellitus in Wistar rats using alloxan is a commonly adopted scientific method for obtaining experimental models. Although a wide variety of induction protocols have been reported, no standard protocol has been defined due to high mortality rates, reversal, and fai...

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Bibliographic Details
Main Authors: Renato de Souza Abboud, Mauricio Alves Chagas, Ilma Cely de Amorim Ribeiro, Lanna Beatriz Neves Silva Corrêa, Raquel Milhomem Lange
Format: Article
Language:English
Published: Universidade Federal Rural de Pernambuco 2020-11-01
Series:Medicina Veterinária
Subjects:
Online Access:https://journals.ufrpe.br/index.php/medicinaveterinaria/article/view/2410