Association between APOL1 risk variants and the occurrence of sepsis in Black patients hospitalized with infections: a retrospective cohort study

Association between APOL1 risk variants and the occurrence of sepsis in Black patients hospitalized with infections: a retrospective cohort study

Background: Two risk variants in the apolipoprotein L1 gene (APOL1) have been associated with increased susceptibility to sepsis in Black patients. However, it remains unclear whether APOL1 high-risk genotypes are associated with occurrence of either sepsis or sepsis-related phenotypes in patients h...

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Bibliographic Details
Main Authors: Lan Jiang, Ge Liu, Annette Oeser, Andrea Ihegword, Alyson L Dickson, Laura L Daniel, Adriana M Hung, Nancy J Cox, Cecilia P Chung, Wei-Qi Wei, C Michael Stein, Qiping Feng
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-10-01
Series:eLife
Subjects:
sepsis
APOL1
African ancestry
electronic health records
Online Access:https://elifesciences.org/articles/88538

Internet

https://elifesciences.org/articles/88538

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