Pathophysiology of lung injury induced by common bile duct ligation in mice.

BACKGROUND: Liver dysfunction and cirrhosis affect vasculature in several organ systems and cause impairment of organ functions, thereby increasing morbidity and mortality. Establishment of a mouse model of hepatopulmonary syndrome (HPS) would provide greater insights into the genetic basis of the d...

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Main Authors: Fumiaki Shikata, Tomohisa Sakaue, Koh-ichi Nakashiro, Mikio Okazaki, Mie Kurata, Toru Okamura, Masahiro Okura, Masahiro Ryugo, Yuki Nakamura, Takumi Yasugi, Shigeki Higashiyama, Hironori Izutani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3986091?pdf=render