Hepatitis B Virus DNA Integration and Clonal Expansion of Hepatocytes in the Chronically Infected Liver

Hepatitis B Virus DNA Integration and Clonal Expansion of Hepatocytes in the Chronically Infected Liver

Human hepatitis B virus (HBV) can cause chronic, lifelong infection of the liver that may lead to persistent or episodic immune-mediated inflammation against virus-infected hepatocytes. This immune response results in elevated rates of killing of virus-infected hepatocytes, which may extend over man...

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Bibliographic Details
Main Authors: William S. Mason, Allison R. Jilbert, Samuel Litwin
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Viruses
Subjects:
hepatitis B virus
virus DNA integration
clonal expansion
hepatocellular carcinoma
immune-mediated killing
hepatocyte proliferation
Online Access:https://www.mdpi.com/1999-4915/13/2/210

Internet

https://www.mdpi.com/1999-4915/13/2/210

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