MiRNA-132 regulates the development of osteoarthritis in correlation with the modulation of PTEN/PI3K/AKT signaling

MiRNA-132 regulates the development of osteoarthritis in correlation with the modulation of PTEN/PI3K/AKT signaling

Abstract Background Osteoarthritis (OA) is a commonly known prevalent joint disease, with limited therapeutic methods. This study aimed to investigate the functions of miRNA-132 (miR-132) in the modulation of PTEN/PI3K/AKT signaling pathway in the development and progression of osteoarthritis. Metho...

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Bibliographic Details
Main Authors: Wei Zhang, Chengfang Hu, Chi Zhang, Congfeng Luo, Biao Zhong, Xiaowei Yu
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Geriatrics
Subjects:
miR-132
Osteoarthritis
Chondrocytes
PTEN/PI3K/AKT signaling pathway
Online Access:https://doi.org/10.1186/s12877-021-02046-8

Internet

https://doi.org/10.1186/s12877-021-02046-8

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