UCP2 promotes NSCLC proliferation and glycolysis via the mTOR/HIF‐1α signaling

UCP2 promotes NSCLC proliferation and glycolysis via the mTOR/HIF‐1α signaling

Abstract Background Metabolic disturbance is a hallmark of cancers. Targeting key metabolic pathways and metabolism‐related molecular could be a potential therapeutic approach. Uncoupling protein 2 (UCP2) plays a pivotal part in the malignancy of cancer and its capacity to develop resistance to phar...

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Bibliographic Details
Main Authors: Cailu Song, Qing Liu, Jing Qin, Lingrui Liu, Zhigang Zhou, Han Yang
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Cancer Medicine
Subjects:
glycolysis
HIF‐1α
mTOR
NSCLC
proliferation
UCP2
Online Access:https://doi.org/10.1002/cam4.6938

Internet

https://doi.org/10.1002/cam4.6938

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