Back to the drawing board: Re-thinking the role of GLI1 in pancreatic carcinogenesis [v1; ref status: indexed, http://f1000r.es/4du]
Aberrant activation of the transcription factor GLI1, a central effector of the Hedgehog (HH) pathway, is associated with several malignancies, including pancreatic ductal adenocarcinoma (PDAC), one of most deadly human cancers. GLI1 has been described as an oncogene in PDAC, making it a promising t...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2014-10-01
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| Series: | F1000Research |
| Subjects: | |
| Online Access: | http://f1000research.com/articles/3-238/v1 |