LC/MS-MS Analysis of Phenolic Compounds in <i>Hyoscyamus albus</i> L. Extract: In Vitro Antidiabetic Activity, In Silico Molecular Docking, and In Vivo Investigation against STZ-Induced Diabetic Mice

LC/MS-MS Analysis of Phenolic Compounds in <i>Hyoscyamus albus</i> L. Extract: In Vitro Antidiabetic Activity, In Silico Molecular Docking, and In Vivo Investigation against STZ-Induced Diabetic Mice

This study aimed to investigate the chemical composition and antidiabetic properties of cultivated <i>Hyoscyamus albus</i> L. The ethanol extract was analyzed using LC-MS/MS, and 18 distinct phenolic compounds were identified. Among these, p-coumaric acid (6656.8 ± 3.4 µg/g), gallic acid...

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Bibliographic Details
Main Authors: Sabrina Lekmine, Ouided Benslama, Kenza Kadi, Antonio Ignacio Martín-García, Mustafa Abdullah Yilmaz, Salah Akkal, Ali Boumegoura, Abdullah S. Alhomida, Mohammad Shamsul Ola, Ahmad Ali
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceuticals
Subjects:
antidiabetic activity
<i>Hyoscyamus albus</i> L.
α-glucosidase
α-amylase
molecular docking
Online Access:https://www.mdpi.com/1424-8247/16/7/1015

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https://www.mdpi.com/1424-8247/16/7/1015

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