MicroRNAs and Metabolites in Serum Change after Chemotherapy: Impact on Hematopoietic Stem and Progenitor Cells.

Hematopoietic regeneration after high dose chemotherapy necessitates activation of the stem cell pool. There is evidence that serum taken after chemotherapy comprises factors stimulating proliferation and self-renewal of CD34(+) hematopoietic stem and progenitor cells (HSPCs)--however, the nature of...

Full description

Bibliographic Details
Main Authors: Thomas Walenda, Yvonne Diener, Edgar Jost, Elizabeth Morin-Kensicki, Tamme W Goecke, Andreas Bosio, Björn Rath, Tim H Brümmendorf, Ute Bissels, Wolfgang Wagner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0128231