High-sensitive spatially resolved T cell receptor sequencing with SPTCR-seq

High-sensitive spatially resolved T cell receptor sequencing with SPTCR-seq

Abstract Spatial resolution of the T cell repertoire is essential for deciphering cancer-associated immune dysfunction. Current spatially resolved transcriptomic technologies are unable to directly annotate T cell receptors (TCR). We present spatially resolved T cell receptor sequencing (SPTCR-seq),...

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Bibliographic Details
Main Authors: Jasim Kada Benotmane, Jan Kueckelhaus, Paulina Will, Junyi Zhang, Vidhya M. Ravi, Kevin Joseph, Roman Sankowski, Jürgen Beck, Catalina Lee-Chang, Oliver Schnell, Dieter Henrik Heiland
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43201-6

Internet

https://doi.org/10.1038/s41467-023-43201-6

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