Dual Role of p53 in Innate Antiviral Immunity

Tumor suppressor p53 is widely known as ‘the guardian of the genome’ due to its ability to prevent the emergence of transformed cells by the induction of cell cycle arrest and apoptosis. However, recent studies indicate that p53 is also a direct transcriptional target of type I interferons (IFNs) an...

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Bibliographic Details
Main Authors: Cesar Munoz-Fontela, Stuart A. Aaronson, Carmen Rivas
Format: Article
Language:English
Published: MDPI AG 2010-01-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/2/1/298/