Characterization of Pyroptosis-Related Subtypes via RNA-Seq and ScRNA-Seq to Predict Chemo-Immunotherapy Response in Triple-Negative Breast Cancer

Characterization of Pyroptosis-Related Subtypes via RNA-Seq and ScRNA-Seq to Predict Chemo-Immunotherapy Response in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is associated with poor prognosis and invalid therapeutical response to immunotherapy due to biological heterogeneity. There is an urgent need to screen for reliable indices, especially immunotherapy-associated biomarkers that can predict patient outcomes. Pyropt...

Full description

Bibliographic Details
Main Authors: Chenlu Li, Jingjing Pan, Yinyan Jiang, Yanzhi Wu, Zhenlin Jin, Xupeng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Genetics
Subjects:
pyroptosis
triple-negative breast cancer
molecular subtype
tumor microenvironment
prognosis
single-cell RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.788670/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.788670/full

Similar Items