Alzheimer’s Disease Pathology in Middle Aged and Older People with HIV: Comparisons with Non-HIV Controls on a Healthy Aging and Alzheimer’s Disease Trajectory and Relationships with Cognitive Function

Alzheimer’s Disease Pathology in Middle Aged and Older People with HIV: Comparisons with Non-HIV Controls on a Healthy Aging and Alzheimer’s Disease Trajectory and Relationships with Cognitive Function

We determined the prevalence of Alzheimer’s disease (AD) pathological hallmarks, amyloid-β and phosphorylated-Tau, in autopsied brains of 49 people with HIV (PWH) (ages: 50–68; mean age = 57.0) from the National NeuroAIDS Tissue Consortium and in a comparative cohort of 55 people without HIV (PWoH)...

Full description

Bibliographic Details
Main Authors: Erin E. Sundermann, Laura M. Campbell, Olivia Villers, Mark W. Bondi, Ben Gouaux, David P. Salmon, Douglas Galasko, Virawudh Soontornniyomkij, Ronald J. Ellis, David J. Moore
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Viruses
Subjects:
HIV
Alzheimer’s disease
pathology
amyloid-beta
tau
cognition
Online Access:https://www.mdpi.com/1999-4915/15/6/1319

Internet

https://www.mdpi.com/1999-4915/15/6/1319

Similar Items