Common-Lymphoid-Progenitor-Independent Pathways of Innate and T Lymphocyte Development

All lymphocytes are thought to develop from common lymphoid progenitors (CLPs). However, lymphoid-primed multipotent progenitors (LMPPs) are more efficient than CLPs in differentiating into T cells and group 2 innate lymphoid cells (ILC2s). Here, we have divided LMPPs into CD127− (LMPP−s) and CD127+...

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Bibliographic Details
Main Authors: Maryam Ghaedi, Catherine A. Steer, Itziar Martinez-Gonzalez, Timotheus Y.F. Halim, Ninan Abraham, Fumio Takei
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716302959