Functional implications of Neandertal introgression in modern humans

Abstract Background Admixture between early modern humans and Neandertals approximately 50,000–60,000 years ago has resulted in 1.5–4% Neandertal ancestry in the genomes of present-day non-Africans. Evidence is accumulating that some of these archaic alleles are advantageous for modern humans, while...

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Bibliographic Details
Main Authors: Michael Dannemann, Kay Prüfer, Janet Kelso
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Genome Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13059-017-1181-7