Paternal phthalate exposure-elicited offspring metabolic disorders are associated with altered sperm small RNAs in mice

Paternal phthalate exposure-elicited offspring metabolic disorders are associated with altered sperm small RNAs in mice

Exposure to ubiquitous plastic-associated endocrine disrupting chemicals (EDCs) is associated with the increased risk of many chronic diseases. For example, phthalate exposure is associated with cardiometabolic mortality in humans, with societal costs ∼ $39 billion/year or more. We recently demonstr...

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Bibliographic Details
Main Authors: Jingwei Liu, Junchao Shi, Rebecca Hernandez, Xiuchun Li, Pranav Konchadi, Yuma Miyake, Qi Chen, Tong Zhou, Changcheng Zhou
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Environment International
Subjects:
Phthalate
Paternal exposure
Transgenerational inheritance
Metabolic disease
Sperm small non-coding RNA
PANDORA-seq
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412023000429

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http://www.sciencedirect.com/science/article/pii/S0160412023000429

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