Immodulin peptides influence musculoskeletal homeostasis by linking extracellular cues to macrophage and myoblast nuclear receptors
Immodulins are synthetic peptides derived from the C-terminal domains of insulin-like growth factor binding proteins (IGFBPs). Immodulins from the 3/5/6 (but not 1/2/4) IGFBP evolutionary clade transduce extracellular matrix (ECM) signals to RXR, NR4A1 and PPAR-alpha nuclear receptors (NRs) to stim...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2022-09-01
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| Series: | European Journal of Translational Myology |
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| Online Access: | https://www.pagepressjournals.org/index.php/bam/article/view/10695 |