In silico and in vivo evaluations of fisetin and fisetin-loaded nanosuspension on monoamine oxidase inhibition in Aβ(25–35) induced dementia in mice model

In silico and in vivo evaluations of fisetin and fisetin-loaded nanosuspension on monoamine oxidase inhibition in Aβ(25–35) induced dementia in mice model

Background: Amyloid beta (Aβ) plaques on the extracellular matrix and intracellular neurofibrillary tangles comprise the key indicative pathology of Alzheimer's disease (AD). Fisetin, an antioxidant bioactive compound having pharmacotherapeutic effects is applied by traditional Chinese medicine...

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Detalhes bibliográficos
Principais autores: Siti Zaidathul Iman Zolkiffly, Mizaton Hazizul Hasan, Siti Azma Jusoh, Ashok Kumar Janakiraman, Sathesh Kumar Sukumaran, Noreen Husain, Yuslina Zakaria, Hanish Singh Jayasingh Chellammal
Formato: Artigo
Idioma:English
Publicado em: Elsevier 2024-12-01
coleção:Pharmacological Research - Modern Chinese Medicine
Assuntos:
Alzheimer's disease
Fisetin
Traditional Chinese medicine
Nanosuspension
Docking studies
Monoamine oxidase
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2667142524001891

Internet

http://www.sciencedirect.com/science/article/pii/S2667142524001891

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