Computational method using heterogeneous graph convolutional network model combined with reinforcement layer for MiRNA–disease association prediction

Abstract Background A large number of evidences from biological experiments have confirmed that miRNAs play an important role in the progression and development of various human complex diseases. However, the traditional experiment methods are expensive and time-consuming. Therefore, it is a challen...

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Bibliographic Details
Main Authors: Dan Huang, JiYong An, Lei Zhang, BaiLong Liu
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-022-04843-3