Validation of HPLC and Liquid-Liquid Extraction Methods for Warfarin Detection in Human Plasma and its Application to a Pharmacokinetics Study
A reversed-phase HPLC method to determine total plasma warfarin was developed and validated. Warfarin was extracted from human plasma using a two-step liquid-liquid extraction method. The residue was reconstituted with a phenylbutazone standard solution, which was used as the internal standard. The...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Academy of Sciences Malaysia
2019-06-01
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| Series: | ASM Science Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.32802/asmscj.2019.215 |