ACLP Activates Cancer-Associated Fibroblasts and Inhibits CD8+ T-Cell Infiltration in Oral Squamous Cell Carcinoma

ACLP Activates Cancer-Associated Fibroblasts and Inhibits CD8+ T-Cell Infiltration in Oral Squamous Cell Carcinoma

We previously showed that upregulation of adipocyte enhancer-binding protein 1 (<i>AEBP1</i>) in vascular endothelial cells promotes tumor angiogenesis. In the present study, we aimed to clarify the role of stromal <i>AEBP1</i>/ACLP expression in oral squamous cell carcinoma...

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Bibliographic Details
Main Authors: Shohei Sekiguchi, Akira Yorozu, Fumika Okazaki, Takeshi Niinuma, Akira Takasawa, Eiichiro Yamamoto, Hiroshi Kitajima, Toshiyuki Kubo, Yui Hatanaka, Koyo Nishiyama, Kazuhiro Ogi, Hironari Dehari, Atsushi Kondo, Makoto Kurose, Kazufumi Obata, Akito Kakiuchi, Masahiro Kai, Yoshihiko Hirohashi, Toshihiko Torigoe, Takashi Kojima, Makoto Osanai, Kenichi Takano, Akihiro Miyazaki, Hiromu Suzuki
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cancers
Subjects:
oral cancer
tumor microenvironment
cancer-associated fibroblast
collagen
tumor-infiltrating lymphocyte
Online Access:https://www.mdpi.com/2072-6694/15/17/4303

Internet

https://www.mdpi.com/2072-6694/15/17/4303

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