In Vivo Tumor Targeting by the B-Subunit of Shiga Toxin

In Vivo Tumor Targeting by the B-Subunit of Shiga Toxin

Delivery of drugs to the appropriate target cells would improve efficacy and reduce potential side effects. The nontoxic B-subunit of the intestinal pathogen-produced Shiga toxin (STxB) binds specifically to the glycosphingolipid Gb 3 , overex-pressed in membranes of certain tumor cells, and enters...

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Bibliographic Details
Main Authors: Thomas Viel, Estelle Dransart, Fariba Nemati, Emilie Henry, Benoit Thézé, Didier Decaudin, Daniel Lewandowski, Raphael Boisgard, Ludger Johannes, Bertrand Tavitian
Format: Article
Language:English
Published: SAGE Publishing 2008-11-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2008.00022

Internet

https://doi.org/10.2310/7290.2008.00022

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