Potentiating humoral and cellular immunity using a novel hybrid polymer-lipid nanoparticle adjuvant for HBsAg-VLP vaccine

Abstract Aluminium adjuvants are commonly used in vaccines to stimulate the immune system, but they have limited ability to promote cellular immunity which is necessary for clearing viral infections like hepatitis B. Current adjuvants that do promote cellular immunity often have undesired side effec...

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Bibliographic Details
Main Authors: Xuhan Liu, Qiuxia Min, Huiping Song, Aochun Yue, Qin Li, Qing Zhou, Wei Han
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-023-02116-6