Pandemic Vibrio cholerae shuts down site-specific recombination to retain an interbacterial defence mechanism

Vibrio cholerae uses a type VI secretion system (T6SS) to kill neighbouring competitors. Here, Santoriello et al. show that a T6SS gene cluster (Aux3) exists as a mobile, prophage-like element in some environmental strains, and as a stable truncated form in pandemic isolates. They propose that Aux3...

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Bibliographic Details
Main Authors: Francis J. Santoriello, Lina Michel, Daniel Unterweger, Stefan Pukatzki
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20012-7