Periostin promotes the proliferation and metastasis of osteosarcoma by increasing cell survival and activates the PI3K/Akt pathway

Periostin promotes the proliferation and metastasis of osteosarcoma by increasing cell survival and activates the PI3K/Akt pathway

Abstract Background Silencing of the periostin gene (POSTN) can inhibit the biological process of several different cancers, and this inhibition may be related to down-regulation of PI3K/AKT signaling. However, the effect of POSTN on the progression, proliferation, and invasion of osteosarcoma (OS)...

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Bibliographic Details
Main Authors: Chaojian Xu, Ziyue Wang, Long Zhang, Yi Feng, Jia Lv, Zhuangzhuang Wu, Rong Yang, Taiyong Wu, Jian Li, Ruhao Zhou, Zhi Tian, Junjun Bai, Huadong Zhang, Yanping Lan, Zhi Lv
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Cancer Cell International
Subjects:
POSTN (Periostin)
Osteosarcoma
Proliferation
Metastasis
Pathway
Online Access:https://doi.org/10.1186/s12935-021-02441-6

Internet

https://doi.org/10.1186/s12935-021-02441-6

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