Quantitative analysis of sensitivity to a Wnt3a gradient in determination of the pole‐to‐pole axis of mitotic cells by using a microfluidic device

Quantitative analysis of sensitivity to a Wnt3a gradient in determination of the pole‐to‐pole axis of mitotic cells by using a microfluidic device

Proper determination of the cell division axis is essential during development. Wnt3a is a known regulator of the cell division axis; however, the sensitivity of cells to Wnt3a signalling and its role in determining the cell division axis have not been measured to date. To address this gap, we took...

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Bibliographic Details
Main Authors: Takumi Hiraiwa, Yuichiro Nakai, Takahiro G. Yamada, Ryuichi Tanimoto, Hiroshi Kimura, Yoshinori Matsumoto, Norihisa Miki, Noriko Hiroi, Akira Funahashi
Format: Article
Language:English
Published: Wiley 2018-12-01
Series:FEBS Open Bio
Subjects:
microfluidics
neuroblastoma
pole‐to‐pole axis
quantitative gradient ODF2
Wnt3a
Online Access:https://doi.org/10.1002/2211-5463.12525

Internet

https://doi.org/10.1002/2211-5463.12525

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