SMARCB1/INI1 loss in skull base conventional chordomas: a clinicopathological and molecular analysis

SMARCB1/INI1 loss in skull base conventional chordomas: a clinicopathological and molecular analysis

IntroductionThe loss of SMARCB1/INI1 protein has been recently described in poorly differentiated chordoma, an aggressive and rare disease variant typically arising from the skull base.MethodsRetrospective study aimed at 1) examining the differential immunohistochemical expression of SMARCB1/INI1 in...

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Bibliographic Details
Main Authors: Alberto Righi, Stefania Cocchi, Margherita Maioli, Matteo Zoli, Federica Guaraldi, Elisa Carretta, Giovanna Magagnoli, Ernesto Pasquini, Sofia Melotti, Gianfranco Vornetti, Caterina Tonon, Diego Mazzatenta, Sofia Asioli
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
skull base
chordoma
prognosis
SMARCB1/INI1
FISH analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1160764/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1160764/full

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