In vitro Evaluation of Antiproliferative Effects of Self-assembling Nanoemulsion of Paclitaxel on Various Cancer Cell Lines

Paclitaxel is routinely used in cancer chemotherapy to treat patients with ovarian, breast, lung, head and neck cancers. However, because of its low aqueous solubility, it’s been administered as a Cremophor EL and ethanol solution, which is associated with increased toxicity and high therapeutic dos...

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Bibliographic Details
Main Authors: Mukta Bagul, Srikanth Kakumanu, Thomas Wilson, Robert Nicolosi
Format: Article
Language:English
Published: Tsinghua University Press 2010-06-01
Series:Nano Biomedicine and Engineering
Subjects:
Online Access:https://www.sciopen.com/article/10.5101/nbe.v2i2.p100-108