miR-124 Inhibits Lung Tumorigenesis Induced by K-ras Mutation and NNK

miR-124 Inhibits Lung Tumorigenesis Induced by K-ras Mutation and NNK

Dysregulated miRNAs play important role in K-ras mutation or smoking caused lung tumorigenesis. Here, we investigate the role and mechanism of miR-124 in K-ras mutation or smoking-caused lung tumorigenesis and evaluate the therapeutic potential of miR-124 agomiR in K-ras mutation or smoking-caused l...

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Bibliographic Details
Main Authors: Hua Jin, Qing Li, Fenghao Cao, Shu-Nan Wang, Ren-Tao Wang, Yun Wang, Qun-You Tan, Cheng-Run Li, Hua Zou, Dong Wang, Cheng-Xiong Xu
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
lung cancer
miR-124
Akt activation
NNK-induced lung cancer
K-ras mutation-induced lung tumorigenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S216225311730255X

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http://www.sciencedirect.com/science/article/pii/S216225311730255X

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