A flowchart for adequate controls in virus-based monosynaptic tracing experiments identified Cre-independent leakage of the TVA receptor in RΦGT mice

Abstract Background A pseudotyped modified rabies virus lacking the rabies glycoprotein (G-protein), which is crucial for transsynaptic spread, can be used for monosynaptic retrograde tracing. By coupling the pseudotyped virus with transgene expression of the G-protein and the avian leukosis and sar...

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Bibliographic Details
Main Authors: Anna Velica, Klas Kullander
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Neuroscience
Subjects:
Online Access:https://doi.org/10.1186/s12868-024-00848-1