Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing

Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing

Abstract Background mRNA processing is an essential step of gene expression; its malfunction can lead to different degrees of physiological disorder from subclinical disease to death. We previously identified Dido1 as a stemness marker and a gene involved in embryonic stem cell differentiation. DIDO...

Full description

Bibliographic Details
Main Authors: Julio Gutiérrez, Karel H. M. van Wely, Carlos Martínez-A
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cell & Bioscience
Subjects:
Dido
Hepatitis
Male sterility
Ataxia
RNA splicing
Readthrough
Online Access:https://doi.org/10.1186/s13578-022-00804-8

Internet

https://doi.org/10.1186/s13578-022-00804-8

Similar Items