ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains

Abstract Background KRAB zinc finger proteins (KZFPs) represent one of the largest families of DNA-binding proteins in vertebrate genomes and appear to have evolved to silence transposable elements (TEs) including endogenous retroviruses through sequence-specific targeting of repressive chromatin st...

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Detalles Bibliográficos
Main Authors: Hui Shi, Ruslan Strogantsev, Nozomi Takahashi, Anastasiya Kazachenka, Matthew C. Lorincz, Myriam Hemberger, Anne C. Ferguson-Smith
Formato: Artigo
Idioma:English
Publicado: BMC 2019-08-01
Series:Epigenetics & Chromatin
Subjects:
Acceso en liña:http://link.springer.com/article/10.1186/s13072-019-0295-4