A transgenic toolkit for visualizing and perturbing microtubules reveals unexpected functions in the epidermis

The physiological functions of microtubules (MTs) are poorly understood in many differentiated cell types. We developed a genetic toolkit to study MT dynamics and function in diverse cells. Using TRE-EB1-GFP mice, we found that MT dynamics are strongly suppressed in differentiated keratinocytes in t...

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Bibliographic Details
Main Authors: Andrew Muroyama, Terry Lechler
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/29834