HCV-Mediated Apoptosis of Hepatocytes in Culture and Viral Pathogenesis.

Chronic Hepatitis C Virus (HCV) infection is associated with progressive liver injury and subsequent development of fibrosis and cirrhosis. The death of hepatocytes results in the release of cytokines that induce inflammatory and fibrotic responses. The mechanism of liver damage is still under inves...

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Bibliographic Details
Main Authors: Erica Silberstein, Laura Ulitzky, Livia Alves Lima, Nicoleta Cehan, Andréa Teixeira-Carvalho, Philippe Roingeard, Deborah R Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4900611?pdf=render