Hydrogels of Polycationic Acetohydrazone-Modified Phosphorus Dendrimers for Biomedical Applications: Gelation Studies and Nucleic Acid Loading

Hydrogels of Polycationic Acetohydrazone-Modified Phosphorus Dendrimers for Biomedical Applications: Gelation Studies and Nucleic Acid Loading

In this work, we report the assemblage of hydrogels from phosphorus dendrimers in the presence of biocompatible additives and the study of their interactions with nucleic acids. As precursors for hydrogels, phosphorus dendrimers of generations 1–3 based on the cyclotriphosphazene core and...

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Bibliographic Details
Main Authors: Evgeny K. Apartsin, Alina E. Grigoryeva, Audrey Malrin-Fournol, Elena I. Ryabchikova, Alya G. Venyaminova, Serge Mignani, Anne-Marie Caminade, Jean-Pierre Majoral
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Pharmaceutics
Subjects:
phosphorus dendrimers
functionalization
Girard reagents
hydrogels
oligonucleotides
Online Access:http://www.mdpi.com/1999-4923/10/3/120

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http://www.mdpi.com/1999-4923/10/3/120

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