MiR-30a-5p Alters Epidermal Terminal Differentiation during Aging by Regulating BNIP3L/NIX-Dependent Mitophagy

Chronological aging is characterized by an alteration in the genes’ regulatory network. In human skin, epidermal keratinocytes fail to differentiate properly with aging, leading to the weakening of the epidermal function. MiR-30a is particularly overexpressed with epidermal aging, but the downstream...

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Bibliographic Details
Main Authors: Fabien P. Chevalier, Julie Rorteau, Sandra Ferraro, Lisa S. Martin, Alejandro Gonzalez-Torres, Aurore Berthier, Naima El Kholti, Jérôme Lamartine
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/5/836