Faster Adaptation in Smaller Populations: Counterintuitive Evolution of HIV during Childhood Infection.
Analysis of HIV-1 gene sequences sampled longitudinally from infected individuals can reveal the evolutionary dynamics that underlie associations between disease outcome and viral genetic diversity and divergence. Here we extend a statistical framework to estimate rates of viral molecular adaptation...
| Autores principales: | , , |
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| Formato: | Artículo |
| Lenguaje: | English |
| Publicado: |
Public Library of Science (PLoS)
2016-01-01
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| Colección: | PLoS Computational Biology |
| Acceso en línea: | http://europepmc.org/articles/PMC4704780?pdf=render |