Co-Incubation with PPARβ/δ Agonists and Antagonists Modeled Using Computational Chemistry: Effect on LPS Induced Inflammatory Markers in Pulmonary Artery

Co-Incubation with PPARβ/δ Agonists and Antagonists Modeled Using Computational Chemistry: Effect on LPS Induced Inflammatory Markers in Pulmonary Artery

Peroxisome proliferator activated receptor beta/delta (PPARβ/δ) is a nuclear receptor ubiquitously expressed in cells, whose signaling controls inflammation. There are large discrepancies in understanding the complex role of PPARβ/δ in disease, having both anti- and pro-effects on inflammation. Afte...

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Bibliographic Details
Main Authors: Noelia Perez Diaz, Lisa A. Lione, Victoria Hutter, Louise S. Mackenzie
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
nuclear receptor
gene transcription
inflammation
molecular docking
PPARβ/δ
Online Access:https://www.mdpi.com/1422-0067/22/6/3158

Internet

https://www.mdpi.com/1422-0067/22/6/3158

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