Efficacy of nerve growth factor antibody in a knee osteoarthritis pain model in mice

Efficacy of nerve growth factor antibody in a knee osteoarthritis pain model in mice

Abstract Background Nerve growth factor (NGF) is not only an important factor in nerve growth but also a major contributor to the production of inflammation. It has been reported that inhibiting NGF could reduce several types of pain in several animal models. Here, we aimed to clarify the efficacy o...

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Bibliographic Details
Main Authors: Masayuki Miyagi, Tetsuhiro Ishikawa, Hiroto Kamoda, Miyako Suzuki, Gen Inoue, Yoshihiro Sakuma, Yasuhiro Oikawa, Sumihisa Orita, Kentaro Uchida, Kazuhisa Takahashi, Masashi Takaso, Seiji Ohtori
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Musculoskeletal Disorders
Subjects:
Nerve growth factor
Anti-nerve growth factor therapy
Knee osteoarthritis
Monoiodoacetate
CatWalk
Calcitonin gene-related peptide
Online Access:http://link.springer.com/article/10.1186/s12891-017-1792-x

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http://link.springer.com/article/10.1186/s12891-017-1792-x

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